EGF-independent activation of cell-surface EGF receptors harboring mutations found in gefitinib-sensitive lung cancer
作者： S H Choi , J M Mendrola , M A Lemmon
关键词: ErbB 、 Tyrosine phosphorylation 、 Platelet-derived growth factor receptor 、 Epidermal growth factor receptor 、 ROR1 、 Biology 、 Cancer research 、 Tyrosine kinase 、 Receptor tyrosine kinase 、 Gefitinib
摘要: … EGF-independent tyrosine phosphorylation of EGFR, and allowed the receptor to promote Ba/F3 cell mitogenesis in the absence of EGF… 125 I-labeled EGF to Ba/F3 cells expressing WT …
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