Metabolic studies on the hypolipidaemic effect of guar gum.

作者: P.R. Turner , J. Tuomilehto , P. Happonen , A.E. La Ville , M. Shaikh

DOI: 10.1016/0021-9150(90)90021-A

关键词: LipoproteinGuar gumApolipoprotein BIntermediate-density lipoproteinInternal medicineLow-density lipoproteinMetabolic disorderCholesterolCrossover studyChemistryEndocrinology

摘要: Abstract The hypolipidaemic effect of guar gum (30 g/day) was examined in a double blind placebo-controlled crossover study 9 patients with primary hyperlipidaemia. treatment periods were six weeks duration. Cholesterol levels low density lipoprotein (LDL) decreased by 11.5% and intermediate (IDL) 10.7%. Plasma cholesterol reduced 9.6% ( P 125 I-labelled LDL showed decrease 21.6% plasma apo B pool size

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