Identifying DNA Methylation Biomarkers of Cancer Drug Response

作者: Sabine Maier , Christina Dahlstroem , Carolina Haefliger , Achim Plum , Christian Piepenbrock

DOI: 10.2165/00129785-200505040-00003

关键词: Cancer epigeneticsBioinformaticsCancer researchDNA damageDNA repairDNA methylationRegulation of gene expressionMethylationDNA mismatch repairBiologyCarcinogenesis

摘要: … drug resistance constitutes a major obstacle to successful cancer therapy. As highlighted in this review, DNA methylation … on response to several major cancer drugs. To improve patient …

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