β-Catenin mutations and aberrant nuclear expression during endometrial tumorigenesis

作者: M Saegusa , M Hashimura , T Yoshida , I Okayasu

DOI: 10.1054/BJOC.2000.1581

关键词: Atypical hyperplasiaMutationCarcinomaCarcinogenesisPoint mutationImmunohistochemistryBiologyBlotGene mutationPathology

摘要: … A possible association between mutations of the β-catenin gene at putative GSK3β phosphorylation … In this study, to clarify the possible role of β-catenin abnormalities, we …

参考文章(36)
David Tarin, Anthony C. Woodman, Yasuhiro Matsumura, Annelies Borgya, Takashi Sugino, Makoto Sugiyama, Kazuhiro Yoshida, Steven Goodison, Analysis of anomalous CD44 gene expression in human breast, bladder, and colon cancer and correlation of observed mRNA and protein isoforms. American Journal of Pathology. ,vol. 149, pp. 1519- 1530 ,(1996)
Setsuo Hirohashi, Takeshi Fukuchi, Shiro Nozawa, Michiie Sakamoto, Hitoshi Tsuda, Keiji Maruyama, β-Catenin Mutation in Carcinoma of the Uterine Endometrium Cancer Research. ,vol. 58, pp. 3526- 3528 ,(1998)
Andrew Berchuck, Jeff Boyd, Molecular basis of endometrial cancer Cancer. ,vol. 76, pp. 2034- 2040 ,(1995) , 10.1002/1097-0142(19951115)76:10+<2034::AID-CNCR2820761321>3.0.CO;2-U
Jeanne Tran Van Nhieu, Claire Angélique Renard, Yu Wei, Daniel Cherqui, Elie Serge Zafrani, Marie Annick Buendia, Nuclear Accumulation of Mutated β-Catenin in Hepatocellular Carcinoma Is Associated with Increased Cell Proliferation American Journal of Pathology. ,vol. 155, pp. 703- 710 ,(1999) , 10.1016/S0002-9440(10)65168-1
R. J. Zaino, R. Kurman, D. Herbold, J. Gliedman, B. N. Bundy, R. Voet, H. Advani, The significance of squamous differentiation in endometrial carcinoma : data from a gynecologic oncology group study Cancer. ,vol. 68, pp. 2293- 2302 ,(1991) , 10.1002/1097-0142(19911115)68:10<2293::AID-CNCR2820681032>3.0.CO;2-V
Jürgen Behrens, Jens P. von Kries, Michael Kühl, Laurakay Bruhn, Doris Wedlich, Rudolf Grosschedl, Walter Birchmeier, Functional interaction of β-catenin with the transcription factor LEF-1 Nature. ,vol. 382, pp. 638- 642 ,(1996) , 10.1038/382638A0