Two new cytotoxic tetracyclic tetraterpenoids from the soft coral Sarcophyton tortuosum.

摘要: Two new cytotoxic tetracyclic tetraterpenoids, methyl tortuoate A (1) and B (2), along with the known sartortuoate (3) were isolated from soft coral Sarcophyton tortuosum. The structures of 1 2 established by spectroscopic methods, mainly on basis 2D NMR techniques, confirmed single-crystal X-ray diffraction analysis. activities these compounds carried out in vitro human nasophyringeal carcinoma (CNE-2) murine lymphocytic leukemia (P-388) tumor cell lines.