Cutaneous side-effects of kinase inhibitors and blocking antibodies
作者： Caroline Robert , Jean-Charles Soria , Alain Spatz , Axel Le Cesne , David Malka
DOI: 10.1016/S1470-2045(05)70243-6
关键词: Sunitinib 、 Cancer 、 Internal medicine 、 Sorafenib 、 Oncology 、 Kinase 、 Imatinib 、 Medicine 、 Imatinib mesylate 、 EGFR inhibitors 、 Blocking antibody 、 Pharmacology
摘要: Although kinase inhibitors raise hope for people with cancer, patients and their clinicians are commonly confronted the cutaneous side-effects that associated use of these drugs. This review is result collaborations between dermatologists, medical oncologists, pathologists, discusses seen after treatment epidermal-growth-factor receptor (EGFR), imatinib, sorafenib, sunitinib. Some caused by agents very distressing, partly because they chronic owing to long duration treatment. Therefore, need early appropriate dermatological management. Moreover, several studies have reported a link antitumour efficacy EGFR side-effects. Elucidation this connection could lead identification crucial predictive factors tumour response.
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