HIV drug resistance mutations in proviral DNA from a community treatment program.
作者： Anne Derache , Hyoung-Shik Shin , Maya Balamane , Elizabeth White , Dennis Israelski
DOI: 10.1371/JOURNAL.PONE.0117430
关键词: Proviral dna 、 Drug resistance 、 RNA extraction 、 HIV drug resistance 、 Virology 、 Antibiotic resistance 、 Pol genes 、 Genotyping 、 Biology 、 Mutation
摘要: Background Drug resistance mutations archived in resting memory CD4+ cells may persist despite suppression of HIV RNA to <50 copies/ml. We sequenced pol gene from proviral DNA among viremic and suppressed patients identify drug mutations.
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