Blood coagulation and intravascular hemolysis.

作者: O. Egeberg

DOI: 10.1080/00365516209079697

关键词: Congenital spherocytic hemolytic anemiaImmunologyCoagulationMedicineIntravascular hemolysisParoxysmal nocturnal hemoglobinuriaFactor VFibrinogenGastroenterologyHemolysisInternal medicineProaccelerin

摘要: The coagulation system was investigated in five patients with hemolytic diseases, three paroxysmal nocturnal hemoglobinuria (PNH) and two congenital spherocytic anemia. A tendency to short cephalin times, high levels of antihemophilic factor (AHA = VIII) fibrinogen observed. results indicate a hypercoagulable state the blood diseases.Experiments were done injections different amounts sterile hemolysed own intravenously into normal persons, investigations plasma clotting before arid after injections. Injection 30 ml citrated persons produced temporary increase AHA, proaccelerin (factor V), top values AHA on second day injection.The lysed direction hypercoagulability seem he agreement findin...

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