Vitamin D Deficiency Is Not Associated with Changes in Retinal Geometric Parameters in Young People with Type 1 Diabetes
作者： Myra Poon , Maria E. Craig , Harleen Kaur , Janine Cusumano , Muhammad Bayu Sasongko
DOI: 10.1155/2013/280691
关键词: Retinal Artery 、 Vitamin D and neurology 、 Retinal Vein 、 Quartile 、 Diabetic retinopathy 、 Ophthalmology 、 vitamin D deficiency 、 Retinal 、 Endocrinology 、 Type 1 diabetes 、 Medicine 、 Internal medicine
摘要: Changes in retinal geometric parameters predict risk and progression of diabetic retinopathy (DR). We have shown that vitamin D deficiency (VDD) is associated with DR. hypothesized VDD mediates changes parameters. Retinal vascular were assessed using a semiautomated computer program photographs from young people type 1 diabetes (T1D) summarized as central arteriolar venular equivalents (CRAE, CRVE), fractal dimension, length-diameter ratio, branching angle curvature tortuosity. Parameters compared between those without DR (25-hydroxyvitamin concentration ≤ 50 nmol/L). also across quartiles levels. Median CRVE was higher patients (median (IQR) 247.3 μm (31.3) versus 238.8 μm (23.5), ). Fractal dimension marginally greater (1.49 (0.06) 1.47 (0.07) There no difference CRAE, CRVE, angle, tortuosity 25OHD. In conclusion, T1D; however, not measures, suggesting an earlier role the time course pathogenesis.
hindawi.com参考文章(24)
Jarmila Vojtková, Miriam Čiljaková, Lenka Vojarová, Katarína Janíková, Zuzana Michnová, Veronika Šagiová, Hypovitaminosis D in children with type 1 diabetes mellitus and its influence on biochemical and densitometric parameters. Acta Medica (Hradec Kralove, Czech Republic). ,vol. 55, pp. 18- 22 ,(2012) , 10.14712/18059694.2015.69
Craig Munns, Margaret R Zacharin, Christine P Rodda, Jennifer A Batch, Ruth Morley, Noel E Cranswick, Maria E Craig, Wayne S Cutfield, Paul L Hofman, Barry J Taylor, Sonia R Grover, Julie A Pasco, David Burgner, Christopher T Cowell, None, Prevention and treatment of infant and childhood vitamin D deficiency in Australia and New Zealand: a consensus statement. The Medical Journal of Australia. ,vol. 185, pp. 268- 272 ,(2006) , 10.5694/J.1326-5377.2006.TB00558.X
Hülya Aksoy, Fatih Akçay, Naciye Kurtul, Orhan Baykal, Bahattin Avci, Serum 1,25 dihydroxy vitamin D (1,25(OH)2D3), 25 hydroxy vitamin D (25(OH)D) and parathormone levels in diabetic retinopathy Clinical Biochemistry. ,vol. 33, pp. 47- 51 ,(2000) , 10.1016/S0009-9120(99)00085-5
Cora McGreevy, David Williams, New Insights About Vitamin D and Cardiovascular Disease: A Narrative Review Annals of Internal Medicine. ,vol. 155, pp. 820- 826 ,(2011) , 10.7326/0003-4819-155-12-201112200-00004
E ALIBRAHIM, K DONAGHUE, S ROGERS, S HING, A JENKINS, A CHAN, T WONG, Retinal vascular caliber and risk of retinopathy in young patients with type 1 diabetes Ophthalmology. ,vol. 113, pp. 1499- 1503 ,(2006) , 10.1016/J.OPHTHA.2006.05.009
Tien Yin Wong, Michael D Knudtson, Ronald Klein, Barbara EK Klein, Stacy M Meuer, Larry D Hubbard, Computer-assisted Measurement of Retinal Vessel Diameters in the Beaver Dam Eye Study: Methodology, Correlation Between Eyes, and Effect of Refractive Errors Ophthalmology. ,vol. 111, pp. 1183- 1190 ,(2004) , 10.1016/J.OPHTHA.2003.09.039
Sophie Louise Rogers, Gabriella Tikellis, Ning Cheung, Robyn Tapp, Jonathan Shaw, Paul Z Zimmet, Paul Mitchell, Jie Jin Wang, Tien Yin Wong, Retinal Arteriolar Caliber Predicts Incident Retinopathy: The Australian Diabetes, Obesity and Lifestyle (AusDiab) Study Diabetes Care. ,vol. 31, pp. 761- 763 ,(2008) , 10.2337/DC07-1622
Tien Yin Wong, Retinal vessel diameter as a clinical predictor of diabetic retinopathy progression: time to take out the measuring tape. Archives of Ophthalmology. ,vol. 129, pp. 95- 96 ,(2011) , 10.1001/ARCHOPHTHALMOL.2010.347
Muhammad Bayu Sasongko, Tien Yin Wong, Kim C. Donaghue, Ning Cheung, Alicia J. Jenkins, Paul Benitez-Aguirre, Jie Jin Wang, Retinal Arteriolar Tortuosity is Associated With Retinopathy and Early Kidney Dysfunction in Type 1 Diabetes American Journal of Ophthalmology. ,vol. 153, pp. 176- 183 ,(2012) , 10.1016/J.AJO.2011.06.005
Muhammad Bayu Sasongko, Jie Jin Wang, Kim C Donaghue, Ning Cheung, Paul Benitez-Aguirre, Alicia Jenkins, Wynne Hsu, Mong-Li Lee, Tien Y Wong, Alterations in Retinal Microvascular Geometry in Young Type 1 Diabetes Diabetes Care. ,vol. 33, pp. 1331- 1336 ,(2010) , 10.2337/DC10-0055