Cytomegalovirus in human brain tumors: Role in pathogenesis and potential treatment options
作者： Cecilia Söderberg-Nauclér , John Inge Johnsen , None
DOI: 10.5493/WJEM.V5.I1.1
关键词: Bioinformatics 、 Pathogenesis 、 Human cytomegalovirus 、 Cancer 、 Medulloblastoma 、 Cancer research 、 Oncovirus 、 Tumor progression 、 Medicine 、 Congenital cytomegalovirus infection 、 Brain tumor
摘要: During the last years increasing evidence implies that human cytomegalovirus (CMV) can be attributed to malignancies arising from numerous tissues. In this perspective, we will review and discuss potential mechanisms through which CMV infection may contribute brain tumors by affecting tumor cell initiation, progression metastasis formation. Recent also suggests anti-CMV treatment results in impaired growth of positive xenografts animal models potentially increased survival glioblastoma patients. Based on these observations high promoting capacity virus, classical novel antiviral therapies against should revisited as they represent a great promise for halting lower cancer deaths.
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