The rheologic properties of erythrocytes: a study using an automated rheoscope
作者： Bransky Avishay , Korin Natanel , Leshansky Alexander , Lanir Naomi , Nemirovski Yael
DOI: 10.1007/S00397-006-0146-7
关键词: Volumetric flow rate 、 Microchannel 、 Biomedical engineering 、 Chemistry 、 Coupling (electronics) 、 SPHERES 、 Shear (sheet metal) 、 Analytical chemistry 、 Hemorheology 、 Rheoscope 、 Deformation (meteorology)
摘要: Red blood cells (RBCs) suspended in a high-viscosity medium were filmed while flowing through microchannel using an automated rheoscope. Under these conditions, erythrocytes take different orientations and undergo varying deformation according to their location the velocity profile. Measurements of mean at several distances from center constant flow rate acquired for normal thalassemia erythrocytes. The measurements demonstrate how diagnosis can be made based on single contrast conventional methods where shear is mechanically controlled. spatial distribution RBCs rigid microspheres (1 μm) measured. maximum slip was found linearly correlated both microspheres. showed enhanced inward lateral migration compared spheres, which attributed RBC deformation. results coupling between mechanical properties motion microvessels.
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