Melanocyte regeneration reveals mechanisms of adult stem cell regulation.

作者: Thomas O’Reilly-Pol , Stephen L. Johnson

DOI: 10.1016/J.SEMCDB.2008.09.007

关键词: Stem cell factorStem cellBiologyCell biologyAdult stem cellImmunologyStem cell transplantation for articular cartilage repairMesenchymal stem cellCellular differentiationRegeneration (biology)Zebrafish

摘要: Utilization of adult stem cells in regenerative therapies may require a thorough understanding the mechanisms that establish, recruit and renew cell, promote differentiation its daughters, or how cell is repressed by target tissue. Regeneration melanocytes regenerating zebrafish caudal fin, following larval melanocyte-specific ablation, recruitment new during pigment pattern metamorphosis each provides evidence for melanocyte (MSCs) support pattern. We discuss MSC regulation provided from analysis normal mutant regeneration these systems, including implications drawn does not simply recapitulate ontogenetic development. These results suggest will provide fine scale dissection establishing regulating cells.

参考文章(35)
Lilianna Solnica-Krezel, Wolfgang Driever, Alexander F. Schier, Efficient recovery of ENU-induced mutations from the zebrafish germline. Genetics. ,vol. 136, pp. 1401- 1420 ,(1994) , 10.1093/GENETICS/136.4.1401
Paul D. Henion, David W. Raible, Christine E. Beattie, Kirsten L. Stoesser, James A. Weston, Judith S. Eisen, Screen for mutations affecting development of zebrafish neural crest Developmental Genetics. ,vol. 18, pp. 11- 17 ,(1996) , 10.1002/(SICI)1520-6408(1996)18:1<11::AID-DVG2>3.0.CO;2-4
Eve M. Mellgren, Stephen L. Johnson, pyewacket, a new zebrafish fin pigment pattern mutant. Pigment Cell Research. ,vol. 19, pp. 232- 238 ,(2006) , 10.1111/J.1600-0749.2006.00311.X
George Streisinger, Charline Walker, Nancy Dower, Donna Knauber, Fred Singer, Production of clones of homozygous diploid zebra fish ( Brachydanio rerio ) Nature. ,vol. 291, pp. 293- 296 ,(1981) , 10.1038/291293A0
E. H. Budi, L. B. Patterson, D. M. Parichy, Embryonic requirements for ErbB signaling in neural crest development and adult pigment pattern formation Development. ,vol. 135, pp. 2603- 2614 ,(2008) , 10.1242/DEV.019299
Derek L. Stemple, David J. Anderson, Isolation of a stem cell for neurons and glia from the mammalian neural crest Cell. ,vol. 71, pp. 973- 985 ,(1992) , 10.1016/0092-8674(92)90393-Q
M. C. Niu, V. C. Twitty, The origin of epidermal melanophores during metamorphosis in Triturus torosus Journal of Experimental Zoology. ,vol. 113, pp. 633- 647 ,(1950) , 10.1002/JEZ.1401130308
Cheng-chen Huang, Nathan D Lawson, Brant M Weinstein, Stephen L Johnson, reg6 is required for branching morphogenesis during blood vessel regeneration in zebrafish caudal fins Developmental Biology. ,vol. 264, pp. 263- 274 ,(2003) , 10.1016/J.YDBIO.2003.08.016