Left Ventricular Mass and Incidence of Coronary Heart Disease in an Elderly Cohort

作者: Daniel Levy

DOI: 10.7326/0003-4819-110-2-101

关键词: Framingham Heart StudyCardiologyInternal medicineRelative riskBlood pressureCohort studyMyocardial infarctionProspective cohort studyFramingham Risk ScoreMedicineCohortGeneral Medicine

摘要: Objective To examine the association of echocardiographically determined left ventricular mass with incidence coronary heart disease in an elderly cohort. Design Cohort study a follow-up period 4 years. Setting Population-based. Subjects Elderly original volunteer subjects Framingham Heart Study who were free clinically apparent disease. This group included 406 men (mean age, 68 years: range, 60 to 90) and 735 women 69 59 90). Measurements main results During years follow-up, events occurred 37 33 women. Baseline was associated both sexes (P less than 0.01). After adjusting for systolic blood pressure, smoking, ratio total/high density lipoprotein cholesterol, relative risk event, per 50 g/m increment mass/height, 1.67 (95% CI, 1.24 2.23) 1.60 1.10 2.32). Conclusions Echocardiographic assessment offers prognostic information beyond that provided by traditional factors, which can improve our ability identify individuals at high These findings may have widespread implications regarding applications echocardiography clinical practice.

参考文章(28)
Freddy Abi-Samra, Fetnat M. Fouad, Yoshiyuki Nakashima, Robert C. Tarazi, Emmanuel L. Bravo, Determinants of left ventricular hypertrophy and function in hypertension American Journal of Cardiology. ,vol. 49, pp. 951- ,(1982) , 10.1016/0002-9149(82)92210-X
BART L. TROY, JOAQUIN POMBO, CHARLES E. RACKLEY, Measurement of Left Ventricular Wall Thickness and Mass by Echocardiography Circulation. ,vol. 45, pp. 602- 611 ,(1972) , 10.1161/01.CIR.45.3.602
Daniel Levy, Keaven M. Anderson, Daniel D. Savage, Susan A. Balkus, William B. Kannel, William P. Castelli, Risk of ventricular arrhythmias in left ventricular hypertrophy: The Framingham Heart Study American Journal of Cardiology. ,vol. 60, pp. 560- 565 ,(1987) , 10.1016/0002-9149(87)90305-5
Robert C. Schlant, Joel M. Felner, Brent A. Blumenstein, Neil B. Shulman, Steven B. Heymsfield, W.Dallas Hall, Gary L. Wollam, Echocardiographic documentation of regression of left ventricular hypertrophy produced by the treatment of essential hypertension American Journal of Cardiology. ,vol. 49, pp. 951- ,(1982) , 10.1016/0002-9149(82)92211-1
WILLIAM B. KANNEL, Electrocardiographic Left Ventricular Hypertrophy and Risk of Coronary Heart Disease Annals of Internal Medicine. ,vol. 72, pp. 813- 822 ,(1970) , 10.7326/0003-4819-72-6-813
Thomas R. Dawber, William B. Kannel, Lorna P. Lyell, AN APPROACH TO LONGITUDINAL STUDIES IN A COMMUNITY: THE FRAMINGHAM STUDY Annals of the New York Academy of Sciences. ,vol. 107, pp. 539- 556 ,(2006) , 10.1111/J.1749-6632.1963.TB13299.X
William B. Kannel, Arthur Schatzkin, Sudden death: Lessons from subsets in population studies Journal of the American College of Cardiology. ,vol. 5, ,(1985) , 10.1016/S0735-1097(85)80545-3
William B. Kannel, HYPERTENSION, BLOOD LIPIDS, AND CIGARETTE SMOKING AS CO-RISK FACTORS FOR CORONARY HEART DISEASE Annals of the New York Academy of Sciences. ,vol. 304, pp. 128- 139 ,(1978) , 10.1111/J.1749-6632.1978.TB25585.X