Coronary artery calcium and incident cerebrovascular events in an asymptomatic cohort. The MESA Study.
作者： Ashleigh O. Gibson , Michael J. Blaha , Martinson K. Arnan , Ralph L. Sacco , Moyses Szklo
DOI: 10.1016/J.JCMG.2014.07.009
关键词: Internal medicine 、 Severity of illness 、 Framingham Risk Score 、 Cardiology 、 Asymptomatic 、 Surgery 、 Predictive value of tests 、 Coronary artery disease 、 Medicine 、 Cohort 、 Stroke 、 Proportional hazards model
摘要: Abstract Objectives This study assessed the predictive value of coronary artery calcium (CAC) score for cerebrovascular events (CVE) in an asymptomatic multiethnic cohort. Background The CAC score, a measure atherosclerotic burden, has been shown to improve prediction heart disease events. However, CVE is unclear. Methods was measured at baseline examination participants (N = 6,779) MESA (Multi-Ethnic Study Atherosclerosis) and then followed average 9.5 ± 2.4 years diagnosis incident CVE, defined as all strokes or transient ischemic attacks. Results During follow-up, 234 (3.5%) adjudicated occurred. In Kaplan-Meier analysis, presence of CAC associated with lower event-free survival versus absence (log-rank chi-square: 59.8, p Conclusions independent predictor improves discrimination afforded by current stroke risk factors Framingham initially adult
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