Evaluating vaccination strategies to control foot-and-mouth disease: a model comparison study.

摘要: Simulation models can offer valuable insights into the effectiveness of different control strategies and act as important decision support tools when comparing evaluating outbreak scenarios strategies. An international modelling study was performed to compare a range vaccination in foot-and-mouth disease (FMD). Modelling groups from five countries (Australia, New Zealand, USA, UK, The Netherlands) participated study. Vaccination is increasingly being recognized potentially tool FMD, although there considerable uncertainty how it should be used. We sought model outputs assess FMD. Using standardized scenario based on data an FMD exercise UK 2010, showed general agreement between respective terms vaccination. Under assumptions, all demonstrated that with 'stamping-out' infected premises led significant reduction predicted epidemic size duration compared strategy alone. For were advantages vaccinating cattle-only rather than species, using 3-km rings immediately around premises, starting earlier programme. This has shown certain are robust even substantial differences configurations. result increase end-user confidence conclusions drawn outputs. These results used develop effective policies for control.