Systems analysis of transcriptome and proteome in retinoic acid/arsenic trioxide-induced cell differentiation/apoptosis of promyelocytic leukemia

作者: P.-Z. Zheng , K.-K. Wang , Q.-Y. Zhang , Q.-H. Huang , Y.-Z. Du

DOI: 10.1073/PNAS.0502825102

关键词: Arsenic trioxideCellular differentiationCancer researchTranscription factorProteomeTranscriptomeAcute promyelocytic leukemiaRetinoic acidTretinoinMolecular biologyBiology

摘要: Understanding the complexity and dynamics of cancer cells in response to effective therapy requires hypothesis-driven, quantitative, and high-throughput measurement of genes and …

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