The let-7 MicroRNA represses cell proliferation pathways in human cells

作者: Charles D. Johnson , Aurora Esquela-Kerscher , Giovanni Stefani , Mike Byrom , Kevin Kelnar

DOI: 10.1158/0008-5472.CAN-07-1083

关键词: Cell growthCell Growth ProcessBiologyCyclin-dependent kinase 6microRNACell divisionCell cycleCellular differentiationCancer stem cellCell biology

摘要: … This work reveals the let-7 microRNA to be a master regulator of cell proliferation pathways. [… cancer cells. We also show that let-7 reduces cell cycle progression of a liver cancer cell line…

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