The Origin and Development of Human Tumors Studied with Cell Markers

作者: Philip J. Fialkow

DOI: 10.1056/NEJM197407042910109

关键词: CancerCarcinogenHomeostasisBiologyGeneticsHormoneStem cell markerGenetic predispositionBioinformaticsGeneral Medicine

摘要: AMONG the more remarkable but least understood homeostatic mechanisms of higher organisms are those that govern tissue development, growth and repair. Considering trillions cells involved complexity duration these processes from fertilization until death, it is surprising functional derangements such as neoplasia do not occur frequently. Even so, cancer one chief causes human suffering and, such, has been subject intense research. In animals, factors genetic predisposition, viruses, radiation, chemicals, dietary components hormones known carcinogens, they have conclusively associated . . .

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