Induction of tumors in mice by genomic hypomethylation.
作者： François Gaudet , J Graeme Hodgson , Amir Eden , Laurie Jackson-Grusby , Jessica Dausman
关键词: DNA methyltransferase 、 Chromosome 15 、 DNA hypomethylation 、 Molecular biology 、 DNA methylation 、 DNMT1 、 Chromosome instability 、 Carcinogenesis 、 Biology 、 Gene rearrangement
摘要: … myc was overexpressed in almost all hypomethylated tumors (15/18 Dnmt1 chip/– , Fig. 3C). … elements in hypomethylated and MMLV-induced tumors. In 3 of 12 MMLV-induced tumors, …
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