Bone Mineral Density and Risk of Heart Failure in Older Adults: The Cardiovascular Health Study

摘要: Background Despite increasing evidence of a common link between bone and heart health, the relationship mineral density (BMD) failure (HF) risk remains insufficiently studied. Methods Results We investigated whether BMD measured by dual‐energy x‐ray absorptiometry was associated with incident HF in an older cohort. Cox models were stratified sex interactions race assessed. examined at total hip femoral neck separately, both continuously World Health Organization categories. Of 1250 participants, 442 (55% women) developed during median follow‐up 10.5 years. In black nonblack women, neither nor significantly HF; there no significant interaction race. men, hip, but not neck, HF, lower higher (hazard ratio, 1.13 [95% CI, 1.01–1.26] per 0.1 g/cm 2 decrement), whereas 0.74 0.59–0.94]). There men osteoporosis. Among osteoporosis 2.83 1.39–5.74]) compared normal BMD. Conclusions adults, association women. Further research is needed to replicate these findings study potential underlying pathways.