Higher New York Heart Association classes and increased mortality and hospitalization in patients with heart failure and preserved left ventricular function.
作者： Ali Ahmed , Wilbert S. Aronow , Jerome L. Fleg
DOI: 10.1016/J.AHJ.2005.03.066
关键词: Severity of illness 、 Heart failure 、 Cardiology 、 Ejection fraction 、 Medicine 、 Cause of death 、 Proportional hazards model 、 Heart disease 、 Stroke volume 、 Surgery 、 Internal medicine 、 Digoxin
摘要: Background The association between higher New York Heart Association (NYHA) class and outcomes in patients with heart failure preserved systolic function is not well known. Methods We performed a retrospective follow-up study of 988 ejection fraction >45% who participated the DIG trial. Using Cox proportional hazard models, we estimated risks all-cause mortality, hospitalization, hospitalization due to worsening during median 38.5 months. Results Patients had age 68 years; 41.2% were women 13.9%, nonwhites. Overall, 23.4% died, 19.9% hospitalized because failure. Proportion NYHA classes I, II, III, IV 19.9%, 58.0%, 20.9%, 1.2%, respectively, 14.7%, 21.1%, 35.9%, 58.3%, died all causes ( P = .042), 2.56 (95% CI 1.64-24.01, .502), 2.27 (1.45-3.56) 018). II through also associated risk hospitalization. Conclusion Higher poorer function.
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