The origin of hydrogen cyanide in breath.

摘要: The excretion of hydrogen cyanide in breath and blood concentrations were measured eight normal subjects. There was no correlation between levels cyanide. Furthermore, calculated from values much lower than values, which suggested a local production the oropharynx. When saliva incubated at 37° C formed presence air but not nitrogen atmosphere. No with boiled by native inhibited catalase 6-n-propyl-thiouracil. Centrifugation resulted supernatant sediment, both required for formation Dialysis abolished its forming ability, could be restored addition thiocyanate. We conclude that most found human beings originates oxidation thiocyanate salivary peroxidase As consequence measurements can only used to detect heavy exposure