Evolution of Myb Proteins
作者： Colin Davidson , Emily Ray , Joseph Lipsick
DOI: 10.1007/978-1-4020-2869-4_1
关键词: DNA 、 Tandem repeat 、 Gene duplication 、 MYB 、 Chromatin 、 DNA-binding protein 、 Genetics 、 Gene 、 SANT domain 、 Biology
摘要: The Myb domain is a highly conserved 50 amino acid motif found in all eukaryotes and often tandem repeats within single protein. DNA binding proteins with three such (3R) are present animals, plants, fungi protists. Invertebrate animals have 3R myb gene, whereas vertebrates studied thus far at least genes. genes of arose by two duplications from B-myb/Dm-myb-like ancestral gene. first duplication appears to resulted neomorphic paralogue central transactivation domain. This new gene then duplicated again give rise A-myb c-myb. An examination wide variety more distantly related domain-containing suggests that the most function may be interaction chromatin rather than DNA.
springer.com
sci-hub.st 参考文章(119)
A.H. Myrset, A. Bostad, N. Jamin, P.N. Lirsac, F. Toma, O.S. Gabrielsen, DNA and redox state induced conformational changes in the DNA-binding domain of the Myb oncoprotein. The EMBO Journal. ,vol. 12, pp. 4625- 4633 ,(1993) , 10.1002/J.1460-2075.1993.TB06151.X
E.W. Lam, R.J. Watson, An E2F-binding site mediates cell-cycle regulated repression of mouse B-myb transcription. The EMBO Journal. ,vol. 12, pp. 2705- 2713 ,(1993) , 10.1002/J.1460-2075.1993.TB05932.X
G. Foos, S. Grimm, K.H. Klempnauer, Functional antagonism between members of the myb family: B-myb inhibits v-myb-induced gene activation. The EMBO Journal. ,vol. 11, pp. 4619- 4629 ,(1992) , 10.1002/J.1460-2075.1992.TB05564.X
Brigitte Ganter, Joseph S. Lipsick, Myb and Oncogenesis Advances in Cancer Research. ,vol. 76, pp. 21- 60 ,(1999) , 10.1016/S0065-230X(08)60773-3
Chin-Hung Sun, Daniel Palm, Andrew G. McArthur, Staffan G. Svärd, Frances D. Gillin, A novel Myb-related protein involved in transcriptional activation of encystation genes in Giardia lamblia Molecular Microbiology. ,vol. 46, pp. 971- 984 ,(2002) , 10.1046/J.1365-2958.2002.03233.X
T Nomura, N Sakai, A Sarai, T Sudo, C Kanei-Ishii, R.G. Ramsay, D Favier, T.J. Gonda, S Ishii, Negative autoregulation of c-Myb activity by homodimer formation through the leucine zipper. Journal of Biological Chemistry. ,vol. 268, pp. 21914- 21923 ,(1993) , 10.1016/S0021-9258(20)80628-0
Olaf Bartsch, Sebastian Horstmann, Kaan Toprak, Karl-Heinz Klempnauer, Stefano Ferrari, Identification of cyclin A/Cdk2 phosphorylation sites in B-Myb. FEBS Journal. ,vol. 260, pp. 384- 391 ,(2001) , 10.1046/J.1432-1327.1999.00191.X
C E Ibanez, J S Lipsick, Structural and functional domains of the myb oncogene: requirements for nuclear transport, myeloid transformation, and colony formation. Journal of Virology. ,vol. 62, pp. 1981- 1988 ,(1988) , 10.1128/JVI.62.6.1981-1988.1988
Q D Ju, B E Morrow, J R Warner, REB1, a yeast DNA-binding protein with many targets, is essential for growth and bears some resemblance to the oncogene myb. Molecular and Cellular Biology. ,vol. 10, pp. 5226- 5234 ,(1990) , 10.1128/MCB.10.10.5226
G Torelli, L Selleri, A Donelli, S Ferrari, G Emilia, D Venturelli, L Moretti, U Torelli, Activation of c-myb expression by phytohemagglutinin stimulation in normal human T lymphocytes. Molecular and Cellular Biology. ,vol. 5, pp. 2874- 2877 ,(1985) , 10.1128/MCB.5.10.2874