Differential expression of three estrogen receptor subtype mRNAs in gonads and liver from embryos to adults of the medaka, Oryzias latipes.

作者: Tapas Chakraborty , Yasushi Shibata , Lin-Yan Zhou , Yoshinao Katsu , Taisen Iguchi

DOI: 10.1016/J.MCE.2010.12.002

关键词: EndocrinologyEstrogen receptorSexual differentiationHatchingEmbryoOocyteDifferential expressionBiologyOryziasEmbryogenesisInternal medicine

摘要: Abstract In fish, estradiol-17β (E2) regulates various reproductive processes by acting through estrogen receptors (ERs). Here, we cloned three ER subtypes from medaka and examined their developmental expression in the gonads liver of genetically females males embryos to adults. During embryogenesis, marked increases ERβ2, but not either ERα or ERβ1, were found female during sex differentiation. E2 treatment induced up-regulation ERβ2 male embryos. adult ovaries, levels high follicles (granulosa cells) oocyte growth. testis, ERβ1 exhibited a distinct peak at 10 days post hatching (dph). liver, very both throughout sampling period with significantly higher 30–50 dph. These findings suggest each action be mediated different types ERs.

参考文章(44)
Hiroshi Urushitani, Makoto Nakai, Hideko Inanaga, Yasuyuki Shimohigashi, Akio Shimizu, Yoshinao Katsu, Taisen Iguchi, Cloning and characterization of estrogen receptor α in mummichog, Fundulus heteroclitus Molecular and Cellular Endocrinology. ,vol. 203, pp. 41- 50 ,(2003) , 10.1016/S0303-7207(03)00118-7
Takashi Todo, Shinji Adachi, Kohei Yamauchi, Molecular cloning and characterization of Japanese eel estrogen receptor cDNA Molecular and Cellular Endocrinology. ,vol. 119, pp. 37- 45 ,(1996) , 10.1016/0303-7207(96)03792-6
Malgorzata Kotula-Balak, Renata Zielińska, Jan Glogowski, Radosław K Kowalski, Beata Sarosiek, Barbara Bilińska, None, Aromatase expression in testes of XY, YY, and XX rainbow trout (Oncorhynchus mykiss). Comparative Biochemistry and Physiology A-molecular & Integrative Physiology. ,vol. 149, pp. 188- 196 ,(2008) , 10.1016/J.CBPA.2007.11.009
Masaru Nakamura, Tohru Kobayashi, Xiao-Tian Chang, Yoshitaka Nagahama, Gonadal sex differentiation in teleost fish Journal of Experimental Zoology. ,vol. 281, pp. 362- 372 ,(1998) , 10.1002/(SICI)1097-010X(19980801)281:5<362::AID-JEZ3>3.0.CO;2-M
Rüdiger W. Schulz, Luiz Renato de França, Jean-Jacques Lareyre, Florence LeGac, Helio Chiarini-Garcia, Rafael Henrique Nobrega, Takeshi Miura, Spermatogenesis in fish. General and Comparative Endocrinology. ,vol. 165, pp. 390- 411 ,(2010) , 10.1016/J.YGCEN.2009.02.013
William Rainey, Raymond Rodgers, Preface to the IssueMolecular and Cellular Endocrinology: Special Issue: Endocrine Cell Lines Molecular and Cellular Endocrinology. ,vol. 228, ,(2004) , 10.1016/J.MCE.2004.10.007
Takeshi Miura, Chiemi Miura, Takashi Ohta, Manal R. Nader, Takashi Todo, Kohei Yamauchi, Estradiol-17β Stimulates the Renewal of Spermatogonial Stem Cells in Males Biochemical and Biophysical Research Communications. ,vol. 264, pp. 230- 234 ,(1999) , 10.1006/BBRC.1999.1494
Jose Eduardo B. Cavaco, Sandra S. Laurentino, Alberto Barros, Mario Sousa, Silvia Socorro, Estrogen Receptors α and β in Human Testis: Both Isoforms are Expressed Systems Biology in Reproductive Medicine. ,vol. 55, pp. 137- 144 ,(2009) , 10.3109/19396360902855733
Takeshi Miura, Takashi Ohta, Chiemi I. Miura, Kohei Yamauchi, Complementary deoxyribonucleic acid cloning of spermatogonial stem cell renewal factor. Endocrinology. ,vol. 144, pp. 5504- 5510 ,(2003) , 10.1210/EN.2003-0800