Antidepressant-like or anxiolytic-like actions of topiramate alone or co-administered with intra-lateral septal infusions of neuropeptide Y in male Wistar rats.

作者: Miguel Molina-Hernández , N. Patricia Téllez-Alcántara , Jorge I. Olivera-Lopez , M. Teresa Jaramillo

DOI: 10.1016/J.PEPTIDES.2010.03.012

关键词: Internal medicineAnxiolytic likeNeuropeptide Y receptorAntidepressant likeEndocrinologyTopiramatePsychologyPharmacologyDesipramineElevated plus maze

摘要: Abstract We tested the effects of intra-lateral septal infusions neuropeptide Y (NPY) combined with systemic injections topiramate in DRL-72 s paradigm and elevated plus-maze test male Wistar rats. Intra-lateral desipramine (5.0 μg/μl; P

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