Estrous cycle variation in anxiolytic-like effects of topiramate in Wistar rats in two animal models of anxiety-like behavior

作者: Miguel Molina-Hernández , N. Patricia Téllez-Alcántara , Jorge I. Olivera-López , M. Teresa Jaramillo

DOI: 10.1016/J.PBB.2012.11.002

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摘要: Abstract The anxiolytic-like effects of topiramate were assessed during several estrous cycle phases in Wistar rats tested two animal models anxiety-like behavior. In a conflict operant test, proestrus, diazepam (1.3, 2.0 mg/kg; P

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