Subclass Distribution of IgG- and IgA-Producing Cells in Secretory Tissues and Alterations Related to Gut Diseases
作者： P. Brandtzaeg , K. Kett , T. O. Rognum
DOI: 10.1007/978-1-4684-5344-7_37
关键词: Mucous membrane of nose 、 Coeliac disease 、 Subclass 、 Antigen 、 Serum iga 、 Carbohydrate composition 、 Distribution (pharmacology) 、 Biology 、 Protein primary structure 、 Immunology
摘要: Both serum IgA and secretory (sIgA) consist of two subclasses, IgAl IgA2, which differ in primary structure, carbohydrate composition, antigenic properties (1). While predominates (about 90%) normal serum, exocrine secretions have been reported to contain a relatively large proportion (30–50%) IgA2 (2,3). It is not known how subclass production regulated; apparently contradictory information about the influence stimuli has published (4–7).
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