BRAF alteration status and the histone H3F3A gene K27M mutation segregate spinal cord astrocytoma histology

Tarik Tihan, Mitchell S. Berger, Susan M. Chang, Michael D. Prados, Joseph Wiemels, John K. Wiencke, Margaret R. Wrensch, Robert B. Jenkins, Jeanette E. Eckel-Passow, Daniel H. Lachance, Annette M. Molinaro, Kyle M. Walsh, Paul A. Decker, Hugues Sicotte, Melike Pekmezci, Terri Rice, Matt L. Kosel, Ivan V. Smirnov, Gobinda Sarkar, Alissa A. Caron, Thomas M. Kollmeyer, Corinne E. Praska, Anisha R. Chada, Chandralekha Halder, Helen M. Hansen, Lucie S. McCoy, Paige M. Bracci, Roxanne Marshall, Shichun Zheng, Gerald F. Reis, Alexander R. Pico, Brian P. O’Neill, Jan C. Buckner, Caterina Giannini, Jason T. Huse, Arie Perry, Glioma Groups Based on 1p/19q, IDH, and TERT Promoter Mutations in Tumors The New England Journal of Medicine. ,vol. 372, pp. 2499- 2508 ,(2015) , 10.1056/NEJMOA1407279

David N. Louis, Arie Perry, Peter Burger, David W. Ellison, Guido Reifenberger, Andreas von Deimling, Kenneth Aldape, Daniel Brat, V. Peter Collins, Charles Eberhart, Dominique Figarella-Branger, Gregory N. Fuller, Felice Giangaspero, Caterina Giannini, Cynthia Hawkins, Paul Kleihues, Andrey Korshunov, Johan M. Kros, M. Beatriz Lopes, Ho-Keung Ng, Hiroko Ohgaki, Werner Paulus, Torsten Pietsch, Marc Rosenblum, Elisabeth Rushing, Figen Soylemezoglu, Otmar Wiestler, Pieter Wesseling, International Society of Neuropathology-Haarlem Consensus Guidelines for Nervous System Tumor Classification and Grading Brain Pathology. ,vol. 24, pp. 429- 435 ,(2014) , 10.1111/BPA.12171

Ganesh M. Shankar, Joshua M. Francis, Mikael L. Rinne, Shakti H. Ramkissoon, Franklin W. Huang, Andrew S. Venteicher, Elliot H. Akama-Garren, Yun Jee Kang, Nina Lelic, James C. Kim, Loreal E. Brown, Sarah K. Charbonneau, Alexandra J. Golby, Chandra Sekhar Pedamallu, Mai P. Hoang, Ryan J. Sullivan, Andrew D. Cherniack, Levi A. Garraway, Anat Stemmer-Rachamimov, David A. Reardon, Patrick Y. Wen, Priscilla K. Brastianos, William T. Curry, Fred G. Barker, William C. Hahn, Brian V. Nahed, Keith L. Ligon, David N. Louis, Daniel P. Cahill, Matthew Meyerson, Rapid Intraoperative Molecular Characterization of Glioma JAMA Oncology. ,vol. 1, pp. 662- 667 ,(2015) , 10.1001/JAMAONCOL.2015.0917

Cancer Genome Atlas Research Network, None, Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas. The New England Journal of Medicine. ,vol. 372, pp. 2481- 2498 ,(2015) , 10.1056/NEJMOA1402121

Jane B. Cryan, Sam Haidar, Lori A. Ramkissoon, Wenya Linda Bi, David S. Knoff, Nikolaus Schultz, Malak Abedalthagafi, Loreal Brown, Patrick Y. Wen, David A. Reardon, Ian F. Dunn, Rebecca D. Folkerth, Sandro Santagata, Neal I. Lindeman, Azra H. Ligon, Rameen Beroukhim, Jason L. Hornick, Brian M. Alexander, Keith L. Ligon, Shakti H. Ramkissoon, Clinical multiplexed exome sequencing distinguishes adult oligodendroglial neoplasms from astrocytic and mixed lineage gliomas Oncotarget. ,vol. 5, pp. 8083- 8092 ,(2014) , 10.18632/ONCOTARGET.2342

, Comprehensive genomic characterization defines human glioblastoma genes and core pathways Nature. ,vol. 455, pp. 1061- 1068 ,(2008) , 10.1038/NATURE07385

Dong-Anh Khuong-Quang, Pawel Buczkowicz, Patricia Rakopoulos, Xiao-Yang Liu, Adam M. Fontebasso, Eric Bouffet, Ute Bartels, Steffen Albrecht, Jeremy Schwartzentruber, Louis Letourneau, Mathieu Bourgey, Guillaume Bourque, Alexandre Montpetit, Genevieve Bourret, Pierre Lepage, Adam Fleming, Peter Lichter, Marcel Kool, Andreas von Deimling, Dominik Sturm, Andrey Korshunov, Damien Faury, David T. Jones, Jacek Majewski, Stefan M. Pfister, Nada Jabado, Cynthia Hawkins, K27M mutation in histone H3.3 defines clinically and biologically distinct subgroups of pediatric diffuse intrinsic pontine gliomas. Acta Neuropathologica. ,vol. 124, pp. 439- 447 ,(2012) , 10.1007/S00401-012-0998-0

David TW Jones, Barbara Hutter, Natalie Jäger, Andrey Korshunov, Marcel Kool, Hans-Jörg Warnatz, Thomas Zichner, Sally R Lambert, Marina Ryzhova, Dong Anh Khuong Quang, Adam M Fontebasso, Adrian M Stütz, Sonja Hutter, Marc Zuckermann, Dominik Sturm, Jan Gronych, Bärbel Lasitschka, Sabine Schmidt, Huriye Şeker-Cin, Hendrik Witt, Marc Sultan, Meryem Ralser, Paul A Northcott, Volker Hovestadt, Sebastian Bender, Elke Pfaff, Sebastian Stark, Damien Faury, Jeremy Schwartzentruber, Jacek Majewski, Ursula D Weber, Marc Zapatka, Benjamin Raeder, Matthias Schlesner, Catherine L Worth, Cynthia C Bartholomae, Christof Von Kalle, Charles D Imbusch, Sylwester Radomski, Chris Lawerenz, Peter Van Sluis, Jan Koster, Richard Volckmann, Rogier Versteeg, Hans Lehrach, Camelia Monoranu, Beate Winkler, Andreas Unterberg, Christel Herold-Mende, Till Milde, Andreas E Kulozik, Martin Ebinger, Martin U Schuhmann, Yoon-Jae Cho, Scott L Pomeroy, Andreas Von Deimling, Olaf Witt, Michael D Taylor, Stephan Wolf, Matthias A Karajannis, Charles G Eberhart, Wolfram Scheurlen, Martin Hasselblatt, Keith L Ligon, Mark W Kieran, Jan O Korbel, Marie-Laure Yaspo, Benedikt Brors, Jörg Felsberg, Guido Reifenberger, V Peter Collins, Nada Jabado, Roland Eils, Peter Lichter, International Cancer Genome Consortium PedBrain Tumor Project Pfister Stefan M s. pfister@ dkfz-heidelberg. de 1 12 b, Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma Nature Genetics. ,vol. 45, pp. 927- 932 ,(2013) , 10.1038/NG.2682

Jinghui Zhang, Gang Wu, Claudia P Miller, Ruth G Tatevossian, James D Dalton, Bo Tang, Wilda Orisme, Chandanamali Punchihewa, Matthew Parker, Ibrahim Qaddoumi, Fredrick A Boop, Charles Lu, Cyriac Kandoth, Li Ding, Ryan Lee, Robert Huether, Xiang Chen, Erin Hedlund, Panduka Nagahawatte, Michael Rusch, Kristy Boggs, Jinjun Cheng, Jared Becksfort, Jing Ma, Guangchun Song, Yongjin Li, Lei Wei, Jianmin Wang, Sheila Shurtleff, John Easton, David Zhao, Robert S Fulton, Lucinda L Fulton, David J Dooling, Bhavin Vadodaria, Heather L Mulder, Chunlao Tang, Kerri Ochoa, Charles G Mullighan, Amar Gajjar, Richard Kriwacki, Denise Sheer, Richard J Gilbertson, Elaine R Mardis, Richard K Wilson, James R Downing, Suzanne J Baker, David W Ellison, St. Jude Children's Research Hospital–Washington University Pediatric Cancer Genome Project, Whole-genome sequencing identifies genetic alterations in pediatric low-grade gliomas Nature Genetics. ,vol. 45, pp. 602- 612 ,(2013) , 10.1038/NG.2611

Catherine S Grasso, Yujie Tang, Nathalene Truffaux, Noah E Berlow, Lining Liu, Marie-Anne Debily, Michael J Quist, Lara E Davis, Elaine C Huang, Pamelyn J Woo, Anitha Ponnuswami, Spenser Chen, Tessa B Johung, Wenchao Sun, Mari Kogiso, Yuchen Du, Lin Qi, Yulun Huang, Marianne Hütt-Cabezas, Katherine E Warren, Ludivine Le Dret, Paul S Meltzer, Hua Mao, Martha Quezado, Dannis G van Vuurden, Jinu Abraham, Maryam Fouladi, Matthew N Svalina, Nicholas Wang, Cynthia Hawkins, Javad Nazarian, Marta M Alonso, Eric H Raabe, Esther Hulleman, Paul T Spellman, Xiao-Nan Li, Charles Keller, Ranadip Pal, Jacques Grill, Michelle Monje, Functionally defined therapeutic targets in diffuse intrinsic pontine glioma Nature Medicine. ,vol. 21, pp. 555- 559 ,(2015) , 10.1038/NM.3855