The role of chromosomal instability in tumor initiation.
作者： M. A. Nowak , N. L. Komarova , A. Sengupta , P. V. Jallepalli , I.-M. Shih
关键词: Cancer 、 Somatic evolution in cancer 、 Genetics 、 Aneuploidy 、 Tumor initiation 、 Loss of heterozygosity 、 Chromosome breakage 、 Biology 、 Tumor progression 、 Chromosome instability
摘要: Chromosomal instability (CIN) is a defining characteristic of most human cancers. Mutation of CIN genes increases the probability that whole chromosomes or large fractions of …
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