Whole genome amplification from a single cell: implications for genetic analysis
作者： L. Zhang , X. Cui , K. Schmitt , R. Hubert , W. Navidi
关键词: MALBAC 、 Gene 、 DNA sequencing 、 Multiple displacement amplification 、 Genome 、 Genetics 、 Biology 、 Whole Genome Amplification 、 Polymerase chain reaction 、 Primer (molecular biology)
摘要: We have developed an in vitro method for amplifying a large fraction of the DNA sequences present in a single haploid cell by repeated primer extensions using a mixture of 15-base …
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Kary B. Mullis, Fred A. Faloona, Specific synthesis of DNA in vitro via a polymerase-catalyzed chain reaction. Methods in Enzymology. ,vol. 155, pp. 335- 350 ,(1987) , 10.1016/0076-6879(87)55023-6
F. S. Collins, M. Boehnke, N. Arnheim, Honghua Li, Fine-structure genetic mapping of human chromosomes using the polymerase chain reaction on single sperm: experimental design considerations. American Journal of Human Genetics. ,vol. 45, pp. 21- 32 ,(1989)
M S Waterman, N Arnheim, W Navidi, A multiple-tubes approach for accurate genotyping of very small DNA samples by using PCR: statistical considerations. American Journal of Human Genetics. ,vol. 50, pp. 347- 359 ,(1992)
Honghua Li, Ulf B. Gyllensten, Xiangfeng Cui, Randall K. Saiki, Henry A. Erlich, Norman Arnheim, Amplification and analysis of DNA sequences in single human sperm and diploid cells Nature. ,vol. 335, pp. 414- 417 ,(1988) , 10.1038/335414A0
M. W. Bradbury, L. M. Isola, J. W. Gordon, Enzymatic amplification of a Y chromosome repeat in a single blastomere allows identification of the sex of preimplantation mouse embryos Proceedings of the National Academy of Sciences of the United States of America. ,vol. 87, pp. 4053- 4057 ,(1990) , 10.1073/PNAS.87.11.4053
Hermann-Josef Lüdecke, Gabriele Senger, Uwe Claussen, Bernhard Horsthemke, Cloning defined regions of the human genome by microdissection of banded chromosomes and enzymatic amplification Nature. ,vol. 338, pp. 348- 350 ,(1989) , 10.1038/338348A0
Alec J. Jeffreys, Victoria Wilson, Rita Neumann, John Keyte, Amplification of human minisatellites by the polymerase chain reaction: towards DNA fingerprinting of single cells Nucleic Acids Research. ,vol. 16, pp. 10953- 10971 ,(1988) , 10.1093/NAR/16.23.10953
Harris A. Lewin, Karin Schmitt, Rene Hubert, Michiel J.T. van Eijk, Norman Arnheim, Close linkage between bovine prolactin and BoLA-DRB3 genes: genetic mapping in cattle by single sperm typing. Genomics. ,vol. 13, pp. 44- 48 ,(1992) , 10.1016/0888-7543(92)90200-C
M. Monk, C. Holding, Amplification of a β-haemoglobin sequence in individual human oocytes and polar bodies The Lancet. ,vol. 335, pp. 985- 988 ,(1990) , 10.1016/0140-6736(90)91060-N
Rene Hubert, Vincent P. Stanton, Hiroyuki Aburatani, John Warren, Honghua Li, David E. Housman, Norman Arnheim, Sperm typing allows accurate measurement of the recombination fraction between D3S2 and D3S3 on the short arm of human chromosome 3. Genomics. ,vol. 12, pp. 683- 687 ,(1992) , 10.1016/0888-7543(92)90294-3