Novel biological therapies for the treatment of diabetic foot ulcers.
作者： Jennifer Adeghate , Syed Nurulain , Kornélia Tekes , Erzsébet Fehér , Huba Kalász
DOI: 10.1080/14712598.2017.1333596
关键词: Surgery 、 Diabetic neuropathy 、 Diabetes mellitus 、 Diabetic angiopathy 、 Medicine 、 American diabetes association 、 Internal medicine 、 Diabetic foot ulcer 、 Diabetic foot 、 Vascular endothelial growth factor 、 Biological therapies
摘要: ABSTRACTIntroduction: The number of people with diabetes mellitus (DM) is estimated to exceed 640 million by the year 2040. Diabetic foot ulcer (DFU) a debilitating illness that affects more than 2% DM patients. DFU caused DM-induced neural and vascular lesions leading reduced sensation microcirculation. increase in prevalence has prompted researchers find new therapies for management DFU.Areas covered: This review presents current status novel biological used treatment DFU. Literature information data analysis were collected from PubMed, website American Diabetes Association, ClinicalTrials.gov. keywords search were: DM, DFU, complications DM.Expert opinion: Many agents have been investigated bid an effective therapy These include growth factors (platelet-derived factor, endothelial factor etc), stem cells (epithelial progenitor-, adipose-d...
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