Morphologic patterns of male infertility in Saudi patients. A University Hospital experience.

作者: Ammar C. Al-Rikabi , Molham M. Al-Rayess

DOI:

关键词: MedicineStage (cooking)BiopsyAplasiaSertoli cell-only syndromeInfertilityHistopathologyMale infertilityPathologyRetrospective cohort study

摘要: OBJECTIVES To determine the predominant histopathological patterns seen in testicular biopsies taken during investigation of male infertility and to compare obtained findings with those other similar studies. METHODS This is a retrospective study performed on 230 which were examined Department Pathology at King Khalid University Hospital Riyadh over period 10 years. The grouped into 8 different morphologic categories. We have utilized classification that principally but uses known or suspected clinical associations case karyotypic abnormalities excurrent duct obstruction. RESULTS Of total studied, 72 cases showed normal spermatogenesis, 50 be associated obstruction. Germinal cell aplasia without focal spermatogenesis was found about 90 cases. Thirty hypospermatogenesis, 25 maturation arrest 12 end stage tubular sclerosis interstitial fibrosis. Only one noted show features abnormalities. CONCLUSIONS A higher percentage germinal this when compared investigations including previous local study. Possible causes these discrepancies may related several factors environmental effects. design studies criteria used for patient selection both could also explain cause observed differences.

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