Changes in patterns of protein synthesis during the mammalian cell cycle.

摘要: Abstract The pattern of protein synthesis during the G2 period interphase in HeLa cells has been compared with an entire cell cycle exponential growth. patterns, as revealed by co-electrophoresis two populations radioactive proteins on acrylamide gels, are very different. differences not due to selective or discontinuous degradation made long short exposures tracer amino acids, nor do they arise from errors method separation and counting. Similar found between other phases a whole, studied pairs. Thus reproductive eukaryotic only involves translational shifts, involvement already known exist consequence studies individual proteins, but it shifts magnitude sufficient for detection bulk soluble proteins.