BRAFV600E Mutation and Its Association with Clinicopathological Features of Colorectal Cancer: A Systematic Review and Meta-Analysis
作者： Dong Chen , Jun-Fu Huang , Kai Liu , Li-Qun Zhang , Zhao Yang
DOI: 10.1371/JOURNAL.PONE.0090607
关键词: MLH1 、 Mutation (genetic algorithm) 、 Pathological staging 、 Internal medicine 、 Meta-analysis 、 Odds ratio 、 CpG Island Methylator Phenotype 、 Colorectal cancer 、 Biology 、 Oncology 、 Microsatellite instability 、 Bioinformatics 、 General Biochemistry, Genetics and Molecular Biology 、 General Agricultural and Biological Sciences 、 General Medicine
摘要: Background Colorectal cancer (CRC) is a heterogeneous disease with multiple underlying causative genetic mutations. The B-type Raf proto-oncogene (BRAF) plays an important role …
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