Novel combi-molecules having EGFR and DNA targeting properties
作者： Zakaria Rachid , Bertrand Jean-Claude , Fouad Brahimi
DOI:
关键词: Stereochemistry 、 Chemical agents 、 Biochemistry 、 EGFR inhibitors 、 DNA 、 Dna targeting 、 Biology 、 Molecule
摘要: A series of new chemical agents that demonstrate anti-tumor activity are described. The combine two major mechanisms action. In an embodiment, the capable both inhibiting EGFR and damaging DNA while also, upon degradation, degrading to inhibitor agent DNA. Moreover, a novel molecules releasing moles potent bi-functional alkylating also
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