Human and mouse cyclin D2 splice variants: transforming activity and subcellular localization

作者: C Denicourt , P Legault , F-A C McNabb , E Rassart

DOI: 10.1038/SJ.ONC.1210750

关键词: Cyclin D2Alternative splicingCyclin D1Cyclin-dependent kinase complexCyclin ABiologyCyclin A2Cyclin DMolecular biologyCyclin-dependent kinase

摘要: Denicourt C, Legault P, McNabb FA, Rassart E. We have previously reported the identification of a novel 17 kDa truncated isoform cyclin D2 activated in 13% leukemias induced by Graffi murine leukemia retrovirus. Retroviral integration Gris1 locus causes an alternative splicing mouse gene and expression protein 159 amino acids that is detected at high levels tumors also normal tissues mainly brain (...)

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