Structural basis of cyclin-dependent kinase activation by phosphorylation.
作者： Alicia A. Russo , Philip D. Jeffrey , Nikola P. Pavletich
DOI: 10.1038/NSB0896-696
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摘要: Cyclin-dependent kinase (CDK)–cyclin complexes require phosphorylation on the CDK subunit for full activation of their Ser/Thr protein kinase activity. The crystal structure of the …
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K.L. Gould, S. Moreno, D.J. Owen, S. Sazer, P. Nurse, Phosphorylation at Thr167 is required for Schizosaccharomyces pombe p34cdc2 function. The EMBO Journal. ,vol. 10, pp. 3297- 3309 ,(1991) , 10.1002/J.1460-2075.1991.TB04894.X
E A Nigg, The substrates of the cdc2 kinase. Seminars in Cell Biology. ,vol. 2, pp. 261- 270 ,(1991)
S Whitehouse, D A Walsh, Mg X ATP2-dependent interaction of the inhibitor protein of the cAMP-dependent protein kinase with the catalytic subunit. Journal of Biological Chemistry. ,vol. 258, pp. 3682- 3692 ,(1983) , 10.1016/S0021-9258(18)32719-4
Wolfram Saenger, Principles of Nucleic Acid Structure ,(1983)
Philip D. Jeffrey, Alicia A. Russo, Kornelia Polyak, Emma Gibbs, Jerard Hurwitz, Joan Massagué, Nikola P. Pavletich, Mechanism of CDK activation revealed by the structure of a cyclinA-CDK2 complex Nature. ,vol. 376, pp. 313- 320 ,(1995) , 10.1038/376313A0
Faming Zhang, Arne Strand, David Robbins, Melanie H. Cobb, Elizabeth J. Goldsmith, Atomic structure of the MAP kinase ERK2 at 2.3 A resolution. Nature. ,vol. 367, pp. 704- 711 ,(1994) , 10.1038/367704A0
Zhou Songyang, Steven Blechner, Nicole Hoagland, Merl F. Hoekstra, Helen Piwnica-Worms, Lewis C. Cantley, Use of an oriented peptide library to determine the optimal substrates of protein kinases Current Biology. ,vol. 4, pp. 973- 982 ,(1994) , 10.1016/S0960-9822(00)00221-9
Tomi P. Mäkelä, Jean-Pierre Tassan, Erich A. Nigg, Séverine Frutiger, Graham J. Hughes, Robert A. Weinberg, A cyclin associated with the CDK-activating kinase MO15 Nature. ,vol. 371, pp. 254- 257 ,(1994) , 10.1038/371254A0
Susan Serota Taylor, Elzbieta Radzio-Andzelm, Three protein kinase structures define a common motif. Structure. ,vol. 2, pp. 345- 355 ,(1994) , 10.1016/S0969-2126(00)00036-8
Robert P. Fisher, David O. Morgan, A novel cyclin associates with M015/CDK7 to form the CDK-activating kinase Cell. ,vol. 78, pp. 713- 724 ,(1994) , 10.1016/0092-8674(94)90535-5