A novel cyclin associates with M015/CDK7 to form the CDK-activating kinase

作者: Robert P. Fisher , David O. Morgan

DOI: 10.1016/0092-8674(94)90535-5

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摘要: Phosphorylation by the CDK-activating kinase (CAK) is a required step in the activation of cyclin-dependent kinases. We have purified CAK from mammalian cells; the enzyme …

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