Protective effects in ambulatory blood pressure and centralized injuries in hydrocephalic Dahl rats on high and low NaCl diets

摘要: Our previous studies in hydrocephalic Dahl rats indicated that the NaCl signal is perceived structures around third brain ventricle. In present study, we assessed 24-h ambulatory blood pressures (ABPs), weight (WT) gains, and kidney injuries induced control group S on 0.3% 6% diets. Constant WT gains were observed among low fed high aqueduct blocked groups, whereas NaCl-fed sham losing dying off after 8 weeks. A circadian BP curve was very distinct from other three groups with markedly increased peak pressure during light cycle amplitude as compared all (both P < .0001). There not only a unstable fluctuating present, but day–night rhythm shift also prominent group. In cross-section, 54 diet for 14 weeks averaged 156 glomeruli. total of 34 fed, 141 glomeruli, 23 102 glomeruli (−28%, cross-section showed many small lacunae truly (193 ± v 77 10 lacunae, 2.5-fold reduction, .0001). The changes may be due to volume electrolyte rebalance reduced volume-controlling center.