Treatment of mandibular atrophy by an equine bone substitute: an immunohistochemical study in man
作者： L. Artese , D.A. Di Stefano , G. Iezzi , M. Piccirilli , S. Pagnutti
DOI: 10.1016/J.IOS.2012.03.008
关键词: Bone regeneration 、 Immunohistochemistry 、 Vascular endothelial growth factor 、 Pathology 、 Regeneration (biology) 、 Bone substitute 、 Nitric oxide synthase 、 Atrophy 、 Medicine 、 Neovascularization
摘要: Abstract Objective To perform an immunohistochemical evaluation of microvessel density (MVD), vascular endothelial growth factor (VEGF) and nitric oxide synthase (NOS) expression in mandibular ridge regeneration using equine-derived bone substitute. Materials methods Ridge augmentations were performed six patients equine bone. After a six-month healing period, four cores from no augmented (control) sites (test) retrieved processed for immunohistochemistry. Results Statistically, significant differences found the MVD between control test (p Conclusions Within limits small sample size, present study indicated that is able to support neovascularization when used as grafting material.
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