Microvessel density and vascular endothelial growth factor expression in sinus augmentation using Bio-Oss.
作者： M Degidi , L Artese , C Rubini , V Perrotti , G Iezzi
DOI: 10.1111/J.1601-0825.2006.01222.X
关键词:
摘要: Aim: The aim of this study was to evaluate microvessel density (MVD) and vascular endothelial growth factor (VEGF) expression in sinus augmentation with Bio-Oss®. Methods: Twenty patients participated study. sinuses were filled 100% Bio-Oss®. Implants inserted after 3 months group A, 6 months B. A trephine used harvest bone cores. As control, the pre-existing subantral used. Results: mean MVD control 23.6 ± 1.8. In sites augmented Bio-Oss®, at 3 months, 23.3 ± 2.1, while retrieved 29.5 ± 2.4. difference between not statistically significant. B significant (P < 0.05). statistical analysis showed that (P < 0.05). Conclusions: Bio-Oss® seemed induce an increase reached a higher value 6 months. percentage vessels positive VEGF than Our data also vessel stromal cells values areas where there newly formed compared maturation processes occuring, fact could point close spatial relationship angiogenesis osteogenesis.
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