Understanding dendritic cell immunotherapy in ovarian cancer

作者: Maureen L. Drakes , Patrick J. Stiff

DOI: 10.1080/14737140.2016.1178576

关键词: Dc vaccineInternal medicineOvarian cancerDendritic cellMedicineImmunotherapyImmunologyT cell immunityDiseaseDrug resistanceOncologyClinical trial

摘要: ABSTRACTIntroduction: Approximately eighty percent of patients with ovarian cancer are diagnosed advanced disease. Even cutting edge surgical techniques and the best regimens standard therapies most relapse die drug resistant disease within five years diagnosis. Dendritic cell (DC) immunotherapy can induce anti-tumor T immunity in holds great potential era modern anti-cancer treatment.Areas Covered: This review outlines critical factors regulating outcome DC cancer, summarizes important findings clinical trials, discusses new directions which may improve effectiveness immunotherapy.Expert Commentary: Administration vaccines other forms enhance efficacy these treatments, ultimately increasing cures for this

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