Targeting strategies on miRNA-21 and PDCD4 for glioblastoma.

作者: Gang Wang , Jun Jie Wang , Hong Ming Tang , Shing Shun Tony To

DOI: 10.1016/J.ABB.2015.07.001

关键词: Downregulation and upregulationBiologySTAT3Transcription factorGliomaPTENCancer researchProgrammed cell deathPI3K/AKT/mTOR pathwaymicroRNABioinformatics

摘要: … These data indicate that a feedback loop exists between miR-21 and EGFR. Thus, the … STAT3 inhibitor WP1066 attenuates miRNA-21 to suppress human oral squamous cell …

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