On the prediction of psd in antisolvent mediated crystallization processes based on fokker-planck equations

作者: M. Grosso , R. Baratti , J. A. Romagnoli

DOI: 10.1590/S0104-66322010000300004

关键词: Fokker–Planck equationComponent (UML)Geometric Brownian motionCrystallizationCrystalStatistical physicsPhysicsCrystal growthThermodynamicsPhenomenological modelParticle-size distribution

摘要: A phenomenological model for the description of antisolvent mediated crystal growth processes is presented. The size dynamics supposed to be driven by a deterministic factor coupled stochastic component. Two different models component are investigated: Linear and Geometric Brownian motion terms. evolution in time particle distribution then described terms Fokker-Planck equation. Validations against experimental data presented NaCl-water-ethanol anti-solvent crystallization system. It was found that proper modeling does have an impact on capabilities fit data. In particular, GBM assumption better suited describe process under examination.

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