The US 2009 A(H1N1) Influenza Epidemic: Quantifying the Impact of School Openings on the Reproductive Number

作者: Karen E. Huang , Marc Lipsitch , Jeffrey Shaman , Edward Goldstein

DOI: 10.1097/EDE.0000000000000055

关键词: A h1n1 influenzaPandemicHuman mortality from H5N1Influenza transmissionVirologyMedicinePopulationOutbreakPandemic influenzaDemographyTransmission (mechanics)

摘要: With the emergence and spread of novel influenza strains having pandemic potential, such as A(H7N9) outbreak in China spring 2013 A(H3N2v) US summer 2012, there is growing need to understand strategies that can slow transmission. One intervention may reduce transmission1–3 -- albeit with high economic social cost1,4,5 school closure. However, are varying estimates change transmission dynamics during time periods when schools open compared they closed.6,7 Such have been often described within limited populations (such a school-based population)8, or regard closures took place epidemic was already declining9. Here we attempt quantify potential effect closure on general population by examining impact beginning year effective reproductive number 2009 A(H1N1) several states.

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