Estrogen Deficiency Induces the Differentiation of IL-17 Secreting Th17 Cells: A New Candidate in the Pathogenesis of Osteoporosis
作者： Abdul M. Tyagi , Kamini Srivastava , Mohd Nizam Mansoori , Ritu Trivedi , Naibedya Chattopadhyay
DOI: 10.1371/JOURNAL.PONE.0044552
关键词: Cellular differentiation 、 Stromal cell 、 Endocrinology 、 RANKL 、 Bone remodeling 、 Osteoclast 、 Bone marrow 、 Osteoblast 、 Bone resorption 、 Biology 、 Internal medicine
摘要: … in IL-17 regulated differentiation of murine osteoclasts and osteoblasts, (ii) proliferation of IL-17 … Our study demonstrated that IL-17 directly stimulated osteoclast differentiation and this …
core.ac.uk
harvard.edu
plosone.org
researchgate.net 参考文章(62)
Agata Kosmaczewska, Jerzy Świerkot, Lidia Ciszak, Piotr Wiland, [The role of Th1, Th17, and Treg cells in the pathogenesis of rheumatoid arthritis including anti-inflammatory action of Th1 cytokines]. Postȩpy higieny i medycyny doświadczalnej. ,vol. 65, pp. 397- 403 ,(2011) , 10.5604/17322693.948971
Jeffrey J Yu, Sarah L Gaffen, Interleukin-17: A novel inflammatory cytokine that bridges innate and adaptive immunity Frontiers in Bioscience. ,vol. 13, pp. 170- 177 ,(2008) , 10.2741/2667
Roberto Pacifici, T cells and post menopausal osteoporosis in murine models. Arthritis Research & Therapy. ,vol. 9, pp. 102- 102 ,(2007) , 10.1186/AR2126
Joseph R. Arron, Yongwon Choi, Bone versus immune system Nature. ,vol. 408, pp. 535- 536 ,(2000) , 10.1038/35046196
Young-Yun Kong, Ulrich Feige, Iidiko Sarosi, Brad Bolon, Anna Tafuri, Sean Morony, Casey Capparelli, Ji Li, Robin Elliott, Susan McCabe, Thomas Wong, Giuseppe Campagnuolo, Erika Moran, Earl R. Bogoch, Gwyneth Van, Linh T. Nguyen, Pamela S. Ohashi, David L. Lacey, Eleanor Fish, William J. Boyle, Josef M. Penninger, Activated T cells regulate bone loss and joint destruction in adjuvant arthritis through osteoprotegerin ligand Nature. ,vol. 402, pp. 304- 309 ,(1999) , 10.1038/46303
Sang-Hyun Kim, Tae-Yong Shin, Amomum xanthiodes inhibits mast cell-mediated allergic reactions through the inhibition of histamine release and inflammatory cytokine production. Experimental Biology and Medicine. ,vol. 230, pp. 681- 687 ,(2005) , 10.1177/153537020523000911
J. C. Holland, O. Brennan, O. D. Kennedy, S. M. Rackard, F. J. O’Brien, T. C. Lee, Subchondral trabecular structural changes in the proximal tibia in an ovine model of increased bone turnover. Journal of Anatomy. ,vol. 218, pp. 619- 624 ,(2011) , 10.1111/J.1469-7580.2011.01376.X
Pamela J. Baker, Mark Dixon, R. Todd Evans, Lisa Dufour, Ellis Johnson, Derry C. Roopenian, CD4+ T Cells and the Proinflammatory Cytokines Gamma Interferon and Interleukin-6 Contribute to Alveolar Bone Loss in Mice Infection and Immunity. ,vol. 67, pp. 2804- 2809 ,(1999) , 10.1128/IAI.67.6.2804-2809.1999
M. Neale Weitzmann, Roberto Pacifici, The role of T lymphocytes in bone metabolism. Immunological Reviews. ,vol. 208, pp. 154- 168 ,(2005) , 10.1111/J.0105-2896.2005.00324.X
Wataru Ariyoshi, Tetsu Takahashi, Takahiro Kanno, Hisashi Ichimiya, Kouhei Shinmyouzu, Hiroshi Takano, Takeyoshi Koseki, Tatsuji Nishihara, Heparin inhibits osteoclastic differentiation and function. Journal of Cellular Biochemistry. ,vol. 103, pp. 1707- 1717 ,(2008) , 10.1002/JCB.21559