Cardiovascular risk stratification in unselected primary care patients with newly detected arterial hypertension

作者: Thomas Dieterle , Joerg-Peter Sigle , Gunar Bengel , Gerrit Kiefer , Verena Brenneisen

DOI: 10.1038/HR.2010.40

关键词: UrinalysisOutpatient clinicAmbulatory blood pressureInternal medicineMicroalbuminuriaBlood pressureDiabetes mellitusMedicineCardiologyRisk assessmentLeft ventricular hypertrophySurgery

摘要: Cardiovascular risk (CVR) stratification in patients with arterial hypertension is essential. Few data are available on CVR factors (CVRFs), hypertensive target organ damage (TOD) and overall medical outpatients newly detected hypertension. General entering the Medical Outpatient Department of University Hospital Basel, Switzerland, were screened for elevated office blood pressure (OBP >140/90 mm Hg). Patients (elevated OBP at two consultations) underwent a work-up that included fundoscopy, urinalysis, ambulatory (ABP) monitoring, ECG echocardiography. was calculated according to 1999/2003 World Health Organization/International Society Hypertension (WHO/ISH) guidelines. A total 2615 screened. Of 580 first OPB, 207 treated hypertension, 98 refused participate, 8 early dropouts 36 had normal second OBP. Data from 212 analyzed (mean age 53+/-14 years). The readings 162+/-6/100+/-6 153+/-14/96+/-9 Hg, respectively. Mean ABP 134+/-12/83+/-9 sustained found 76.9% patients. Among OPB 61.3% 1 or 2 CVRFs, 33.0% >or=3 CVRFs. Evidence TOD, diabetes associated clinical conditions (ACCs), such as renal cardiovascular disease, 26.4, 5.6 7.1% patients, In terms CVR, 2.4% low risk, 25.9% medium 71.7% high risk. No differences existed between white coat hypertensives regarding TOD ACCs. Comprehensive analysis revealed surprisingly prevalence ACCs, indicating majority these

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