Electron Beam CT and Coronary Calcium Score

摘要: To the Editors: I read with enthusiasm recent article by Secci et al.1 This prospective study using electron beam CT (EBCT) and coronary calcium score was done in 326 mostly elderly (mean age, 66±8 years) men (82%). Hypertension (50%) family history of disease (44%) were common, but lipids average (LDL 144±37 mg/dL, HDL 54±14 mg/dL). The 10-year Framingham risk 19±9%. Each followed up for 32 months after EBCT or until documentation a hard (death, infarction) soft (need revascularization) event. Dividing results into quartiles score, al found clear trend more total events those scores above median. When separated, there still significantly when However, despite greater number subjects highest quartile, especially compared lowest no significant alone. My comments relate to four important issues not raised discussion. First, amount calcified plaque correlates, albeit as an underestimation, atherosclerotic burden (lipid-rich, fibrotic, fibrotic plaques) shown histological2 3 ultrasonic4 5 studies. …