Isolation and Culture of Microvascular Endothelial Cells from Gliomas of Different WHO Grades

作者: Sabine Miebach , Stefan Grau , Vera Hummel , Peter Rieckmann , Joerg-Christian Tonn

DOI: 10.1007/S11060-005-3674-6

关键词: MalignancyPathologyPrimary tumorBrain tumorEndothelial stem cellCell cultureBiologyAngiogenesisEndotheliumGlioma

摘要: Gliomas are the most common intrinsic brain tumors. The degree of vascularization corresponds to malignancy and is related prognosis. In order retrieve information about tumor behavior in situ, use primary tissue material for experiments advantageous. With increasing evidence importance microenvironment biology, we concentrated on isolation endothelial cells (EC) from investigate role endothelium within tissue.

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