Histone arginine methylation keeps RUNX1 target genes in an intermediate state.

Wouter de Laat, Petra Klous, Jurgen Kooren, Daan Noordermeer, Robert‐Jan Palstra, Marieke Simonis, Erik Splinter, Frank Grosveld, Three-dimensional organization of gene expression in erythroid cells. Current Topics in Developmental Biology. ,vol. 82, pp. 117- 139 ,(2008) , 10.1016/S0070-2153(07)00005-1

Woo-Joo Song, Melanie G. Sullivan, Robert D. Legare, Sarah Hutchings, Xiaolian Tan, Dubravka Kufrin, Janina Ratajczak, Isabel C. Resende, Catherine Haworth, Randy Hock, Mignon Loh, Carolyn Felix, Denis-Claude Roy, Lambert Busque, David Kurnit, Cheryl Willman, Alan M. Gewirtz, Nancy A. Speck, John H. Bushweller, Frederick P. Li, Katheleen Gardiner, Mortimer Poncz, John M. Maris, D. Gary Gilliland, Haploinsufficiency of CBFA2 causes familial thrombocytopenia with propensity to develop acute myelogenous leukaemia Nature Genetics. ,vol. 23, pp. 166- 175 ,(1999) , 10.1038/13793

Bradley E. Bernstein, Tarjei S. Mikkelsen, Xiaohui Xie, Michael Kamal, Dana J. Huebert, James Cuff, Ben Fry, Alex Meissner, Marius Wernig, Kathrin Plath, Rudolf Jaenisch, Alexandre Wagschal, Robert Feil, Stuart L. Schreiber, Eric S. Lander, A Bivalent Chromatin Structure Marks Key Developmental Genes in Embryonic Stem Cells Cell. ,vol. 125, pp. 315- 326 ,(2006) , 10.1016/J.CELL.2006.02.041

Keith Orford, Peter Kharchenko, Weil Lai, Maria Carlota Dao, David J. Worhunsky, Adam Ferro, Viktor Janzen, Peter J. Park, David T. Scadden, Differential H3K4 methylation identifies developmentally poised hematopoietic genes. Developmental Cell. ,vol. 14, pp. 798- 809 ,(2008) , 10.1016/J.DEVCEL.2008.04.002

Yusuke Satoh, Itaru Matsumura, Hirokazu Tanaka, Sachiko Ezoe, Kentaro Fukushima, Masahiro Tokunaga, Masato Yasumi, Hirohiko Shibayama, Masao Mizuki, Takumi Era, Tsukasa Okuda, Yuzuru Kanakura, AML1/RUNX1 Works as a Negative Regulator of c-Mpl in Hematopoietic Stem Cells Journal of Biological Chemistry. ,vol. 283, pp. 30045- 30056 ,(2008) , 10.1074/JBC.M804768200

Lan Wang, Gang Huang, Xinyang Zhao, Megan A. Hatlen, Ly Vu, Fan Liu, Stephen D. Nimer, Post-translational modifications of Runx1 regulate its activity in the cell Blood Cells Molecules and Diseases. ,vol. 43, pp. 30- 34 ,(2009) , 10.1016/J.BCMD.2009.03.005

Q. Wang, T. Stacy, M. Binder, M. Marin-Padilla, A. H. Sharpe, N. A. Speck, Disruption of the Cbfa2 gene causes necrosis and hemorrhaging in the central nervous system and blocks definitive hematopoiesis. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 93, pp. 3444- 3449 ,(1996) , 10.1073/PNAS.93.8.3444

Ernesto Guccione, Christian Bassi, Fabio Casadio, Francesca Martinato, Matteo Cesaroni, Henning Schuchlautz, Bernhard Lüscher, Bruno Amati, Methylation of histone H3R2 by PRMT6 and H3K4 by an MLL complex are mutually exclusive Nature. ,vol. 449, pp. 933- 937 ,(2007) , 10.1038/NATURE06166

Hideyuki Oguro, Jin Yuan, Hitoshi Ichikawa, Tomokatsu Ikawa, Satoshi Yamazaki, Hiroshi Kawamoto, Hiromitsu Nakauchi, Atsushi Iwama, Poised Lineage Specification in Multipotential Hematopoietic Stem and Progenitor Cells by the Polycomb Protein Bmi1 Cell Stem Cell. ,vol. 6, pp. 279- 286 ,(2010) , 10.1016/J.STEM.2010.01.005

Maarten Hoogenkamp, Hanna Krysinska, Richard Ingram, Gang Huang, Rachael Barlow, Deborah Clarke, Alexander Ebralidze, Pu Zhang, Hiromi Tagoh, Peter N. Cockerill, Daniel G. Tenen, Constanze Bonifer, The Pu.1 locus is differentially regulated at the level of chromatin structure and noncoding transcription by alternate mechanisms at distinct developmental stages of hematopoiesis. Molecular and Cellular Biology. ,vol. 27, pp. 7425- 7438 ,(2007) , 10.1128/MCB.00905-07